Crystal structure of human RBM7 revealed

The crystal structure of the RRM domain of human RBM7 from the nuclear exosome targeting (NEXT) complex). Sofos et al. (2016)

The crystal structure of the RRM domain of human RBM7 from the nuclear exosome targeting (NEXT) complex). Sofos et al. (2016)

Today, we have published a paper in Acta Cryst. Section F presenting the crystal structure of the RNA recognition motif (RRM) domain of human RBM7, a central component of the human nuclear exosome targeting (NEXT) complex.

The crystal structure reveals an unexpected pentameric assembly of the RRM domain, which has been highlighed on the cover of the journal.

For more information, have a look at the paper in Acta Crystallographica Section F.

Sofos, N., Winkler, M. B. L., and Brodersen, D. E. (2016) “RRM domain of human RBM7: purification, crystallization and structure determination”, Acta Cryst., F72:397-402.